基于网络的华法林管理 (Alfalfa App) 与传统的华法林管理:多中心前性队列研究
Wenfei Chen1, Jiana Chen1, Shaojun Jiang1
1Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Journal of medical Internet research
|July 29, 2024
概括
使用Alfalfa应用程序的基于网络的华法林管理可以改善抗凝血控制,并减少相比传统门诊护理的轻微出血事件. 这种数字化方法提高了患者的治疗成果和管理效率.
科学领域:
- 心脏病学 心脏病学
- 数字健康数字健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 华法林抗凝管理对于预防不良事件,住院和死亡至关重要.
- 传统的门诊在提供最佳华法林管理方面面临挑战.
- 需要更安全,更有效,更方便的华法林管理策略.
研究的目的:
- 为了比较基于网络 (Alfalfa应用程序) 和传统非基于网络的模型之间的抗凝管理质量和临床结果.
- 评估数字与传统华法林管理的有效性和安全性.
- 评估治疗范围 (TTR) 和不良事件的时间差异.
主要方法:
- 未来的,多中心的队列研究.
- 患者被分为基于网络 (Alfalfa应用程序) 和非基于网络的管理组.
- 六个月的随访监测了凝血测试和临床事件,包括出血和血栓塞栓事件.
主要成果:
- 基于网络的组显示显著更高的TTR (82.4%对71.6%) 和有效管理率 (81.2%对63.5%).
- 在基于网络的组中,轻微出血事件的频率较低 (6.6%对12.1%).
- 在严重出血,血栓塞栓事件或全因死亡率方面没有发现显著差异.
结论:
- 通过Alfalfa应用程序的基于网络的管理提高了抗凝质量和患者安全.
- 这种数字模型减少了轻微的出血事件,并改善了国际正常化比率 (INR) 的分布.
- 与传统的非基于网络的管理相比,Alfalfa应用程序提供了更有利的方法.
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