在患有系统性红斑狼的住院患者中,脆弱状态和再入院之间的关联
Christopher Leung1, Waqas Tahir2, Yenny Rosli3
1Georgetown University School of Medicine, Washington, DC.
ACR open rheumatology
|July 29, 2024
概括
系统性红斑狼 (SLE) 患者的虚弱与增加的再入院和更高的成本有关. 识别脆弱性有助于预测SLE患者的不良结果.
科学领域:
- 类风湿病学 类风湿病学
- 老年病的医生 老年病的医生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 系统性红斑狼 (SLE) 是一种慢性自身免疫性疾病,具有显著的医疗利用.
- 虚弱是一种新兴的老年综合征,与不良健康结果相关.
研究的目的:
- 调查SLE入院患者的脆弱性和不良结果之间的关联.
- 确定脆弱性是否预测SLE患者的再接收风险,住院死亡率和住院费用.
主要方法:
- 使用国家再接收数据库 (NRD) 进行回顾性队列研究.
- 使用ICD-10代码识别了患有SLE的成年患者.
- 使用医院脆弱风险评分 (HFScore) 评估脆弱性.
- 使用考克斯的比例危险模型分析了再接收率,住院患者死亡率和住院费用.
主要成果:
- 包括39738名SLE患者;18385人被归类为脆弱.
- 脆弱的SLE患者表现出更高的并发症得分和更长的住院时间.
- 脆弱性独立地与10%的再入院风险增加有关.
- 脆弱患者的再入院率更高,住院时间更长,费用增加.
结论:
- 虚弱是住院SLE患者不良结果的重要预测因素.
- 脆弱性评估可以帮助SLE患者的风险分层.
- 识别脆弱的SLE患者可以进行有针对性的干预,以减少再入院和死亡率.
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