使用修改后的米兰系统重新评估骨和软组织细胞病理学分类
Masaki Naka1, Hidetaka Yamamoto1,2,3, Kenichi Kohashi2,4
1Division of Diagnostic Pathology, Kyushu University Hospital, Fukuoka, Japan.
Cancer cytopathology
|July 29, 2024
概括
经过修改的米兰系统和世界卫生组织 (WHO) 的系统显示出对骨和软组织瘤的分类有希望. 这两种系统都在通过细针吸收细胞学诊断恶性瘤方面表现出高准确性.
科学领域:
- 细胞病理学 细胞病理学
- 在瘤学瘤学.
- 组织病理学 组织病理学
背景情况:
- 缺乏骨和软组织瘤细胞病理学的标准化报告系统.
- 这项研究探讨了针对唾液腺细胞病理学的修改后的米兰系统和即将推出的世界卫生组织 (WHO) 软组织病变系统.
研究的目的:
- 评估修改后的米兰系统对骨和软组织病变的分类的有用性.
- 为了将这种修改后的系统与即将发布的世界卫生组织软组织细针吸收分类进行比较.
主要方法:
- 审查了285个骨/关节 (173) 和软组织 (112) 病变的细胞学病例.
- 使用修改的米兰系统分类病例,并将结果与组织学诊断和恶性瘤 (ROM) 风险进行比较.
- 分析了诊断可靠性,并与世卫组织系统进行了比较.
主要成果:
- 所有病例都成功地被分类为从非诊断到恶性的不同类别.
- 经过修改的米兰系统显示了不同类别的ROM值,恶性病变的ROM值为100%.
- 诊断准确度,敏感度和针对恶性瘤检测的特异性都很高 (分别为99.4%,100%和98.0%).
结论:
- 修改后的米兰系统是对骨和软组织病变的潜在有用的细胞病理学分类工具.
- 世卫组织系统似乎也是一个有价值的工具,用于细胞病理学分类在这个领域.
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