氨酸对益生菌生长的影响
Mohammed Nadeem Bijle1, Mohamed Mahmoud Abdalla2, Cynthia Yiu1
1Faculty of Dentistry, The University of Hong Kong, Hong Kong.
Journal of dentistry
|July 29, 2024
概括
补充素 (Arg) 选择性地影响益生菌的生长. 较高的Arg度促进了Lacticaseibacillus rhamnosus GG的生长,同时抑制了Lactiplantibacillus plantarum的生长,这表明度依赖的效果.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 生物技术是生物技术.
背景情况:
- 益生菌是提供健康益处的活微生物.
- 氨酸 (Arg) 是一种具有潜在益生菌特性的氨基酸.
- 了解Arg对特定益生菌菌株的影响对于共生菌的发展至关重要.
研究的目的:
- 调查阿金宁补充剂对选定益生菌菌株生长的影响.
- 为了确定Arg对Lacticaseibacillus rhamnosus GG和Lactiplantibacillus plantarum的度依赖作用.
主要方法:
- 益生菌L. rhamnosus GG和L. plantarum被用不同的Arg度 (0.5%和1.0%) 治疗.
- 评估了生长特征,度,代谢活动 (XTT,WST-8试验) 和殖民地形成单位 (CFU).
- 使用共聚焦激光扫描显微镜 (CLSM) 进行活细胞/死细胞评估.
主要成果:
- 补充氨酸证明了对益生菌生长的菌株特异性影响.
- 增加Arg度促进了L. rhamnosus GG的活力和生长.
- 相反,Arg以度依赖的方式抑制了L. plantarum的生长和活力.
结论:
- 素作为益生菌的选择性生长调节剂,促进L. rhamnosus GG,同时抑制L. plantarum.
- 这些发现强调了对Arg的菌株特异性反应在设计有效的共生配方时的重要性.
- 基于的协生菌可能为调节生物膜环境提供有针对性的方法.
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