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Updated: Jun 18, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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作为潜在的ERK2抑制剂,天然存在的植物性抗癌候选物:基数据库采矿和分子动力学模拟

Mahmoud A A Ibrahim1,2, Sara S M Ali1, Alaa H M Abdelrahman1

  • 1Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, 61519, Egypt.

Chemistry & biodiversity
|July 29, 2024
PubMed
概括

我们选了1500多种植物化合物,寻找潜在的细胞外信号调节激酶2 (ERK2) 抑制剂. 尚库酸C显示出优越的结合亲和力和最小的毒性,表明它是一个有前途的ERK2抑制剂候选者.

关键词:
细胞外信号调节激酶2 (ERK2) 是一种细胞外信号调节激酶.在 NPACT 数据库中.抗癌药物是一种抗癌药物.数据库采矿数据库采矿分子动力学模拟模拟

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