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通过广泛的OB折叠识别tRNA的结构基础

Aline Umuhire Juru1, Rodolfo Ghirlando1, Jinwei Zhang2

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.

Nature communications
|July 29, 2024
PubMed
概括

寡核酸/寡糖酸结合 (OB) 折叠蛋白Trbp通过结合它们的3'端,特别是保存的CA二核酸,来识别转移RNA (tRNA). 这揭示了蛋白质如何与必不可少的RNA分子相互作用的新机制.

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