相关实验视频

Updated: Jun 18, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

在野生动物社区中广泛接触SARS-CoV-2

Amanda R Goldberg¹, Kate E Langwig¹, Katherine L Brown^2,3,4

¹Department of Biological Sciences, Virginia Tech, Blacksburg, VA, USA.

Nature communications

|July 29, 2024

概括

SARS-CoV-2 已经蔓延到许多野生动物物种,包括鹿鼠和子. 人类活动较高的地区显示动物病毒暴露增加,表明潜在的跨物种传播风险.

科学领域:

兽医医学兽医医学兽医医学
野生动物生态生态学
传染性疾病传染性疾病

背景情况:

人类感染SARS-CoV-2导致动物传播.
虽然SARS-CoV-2可以感染许多动物物种,但记录的病例主要发生在被囚禁的动物和白尾鹿中.
野生动物中SARS-CoV-2暴露的全部范围和影响传播风险的因素尚未完全理解.

研究的目的:

调查SARS-CoV-2在各种野生动物群体中的流行情况.
评估城市化和人类活动对野生动物血清阳性的影响.
识别暴露于SARS-CoV-2的野生动物物种并分析传播动态.

主要方法:

从弗吉尼亚州和华盛顿特区的23种野生动物物种收集样本 (2022年5月至2023年9月).
经过SARS-CoV-2RNA和抗体 (血清阳性) 测试.
分析了人类活动水平和血清流行率之间的相关性.
在阳性样本上进行基因组测序,以确定病毒系.

主要成果:

在六种物种中检测到SARS-CoV-2RNA:鹿鼠,弗吉尼亚野,子,土狼,东方棉尾和东方红蝙蝠.
人类大量使用地区的野生动物种群的血清流行率比使用较少的地区高三倍.
基因组测序揭示了来自六种物种的九个个体的Omicron变异的七个Pango血统.
确定了最近至少七起人对动物的SARS-CoV-2传播事件.

结论:

在野生动物社区中,SARS-CoV-2暴露很普遍.
人类活动较多的地区作为SARS-CoV-2从人到野生动物传播的热点.
对SARS-CoV-2的野生动物的持续监测至关重要,特别是在人类主导的景观中.

更多相关视频

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

相关概念视频

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

Threats to Biodiversity

Threats to Biodiversity

There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...

Conservation of Small Populations

Conservation of Small Populations

Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...