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Updated: Jun 18, 2025

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
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检查稳定性聚乙烯醇稳定纳米悬浮,以克服药物溶解性差的挑战,利用分子动态模拟

Sedigheh Abdollahi1, Heidar Raissi2, Farzaneh Farzad1

  • 1Department of Chemistry, University of Birjand, Birjand, Iran.

Scientific reports
|July 29, 2024
PubMed
概括

聚乙醇 (PVA) 有效地稳定了溶解不良药物的纳米悬浮物,提高了药物的溶解性. 分子动力学模拟显示了PVA和特定药物 (如flurbiprofen) 之间的强烈相互作用,改善了配方的稳定性.

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