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乳房保护疗法与乳房切除术后的乳房重建:倾向性得分匹配分析

Minji Kim¹, Audree B Tadros², Lillian A Boe³

¹Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Annals of surgical oncology

|July 29, 2024

概括

乳腺保护疗法 (BCT) 与乳房切除术后乳房重建 (PMBR) 相比,导致更好的患者报告结果 (PROs). 在三年随访期间,BCT患者报告生活质量和满意度更高.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
患者报告的研究结果研究结果

背景情况:

乳房保护疗法 (BCT) 和乳房切除术后乳房重建 (PMBR) 之间的患者报告结果 (PROs) 的直接比较往往因治疗变化而混.
倾向性得分匹配分析被用来使BCT和PMBR之间的PRO能够更直接地比较.

研究的目的:

使用倾向分数匹配分析,比较乳腺保护疗法 (BCT) 和乳腺切除术后乳腺重建 (PMBR) 之间的患者报告结果 (PROs).
随着时间的推移,确定BCT和PMBR患者之间的生活质量,满意度和幸福感的差异.

主要方法:

利用倾向性得分匹配来比较2010-2022年2616名独特患者 (BCT与PMBR) 的情况.
在多个时间点使用BREAST-Q收集的PROs:手术前,6个月和1,2,3年的术后.
在BREAST-Q领域的4点差异被认为是临床上有意义的.

主要成果:

在术后6个月,BCT患者报告了与PMBR患者相比,在所有BREAST-Q领域的得分显著更高.
术后1至3年,BCT患者始终表现出对乳房,心理社会福祉和性福祉的优越满意度.
在关键的PRO领域的这些差异具有临床意义,超过了4点的值.

结论:

乳腺保护疗法 (BCT) 与乳房切除术后乳房重建 (PMBR) 相比,在术后早期和长达三年的时间内,与患者报告的优异结果 (PROs) 相关.
鉴于可比的生存率和复发率,符合两种程序的患者应被告知BCT在PROs方面的优势.
这项研究提供了支持BCT的统计数据支持证据,以改善长期生活质量和患者满意度.

关键词:

乳腺癌乳腺癌乳腺癌乳房重建乳房重建乳腺保护疗法是一种疗法.患者报告的结果乳房切除术后的情况倾向性匹配的比赛.

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