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Updated: Jun 18, 2025

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OLFM4通过促进IL-22在肠道中的ILC3来调节肠道炎症

Zhe Xing1, Xinyao Li2, Junyu He2

  • 1Pediatric Intensive Care Unit, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences); Department of Immunology, School of Basic Medical Sciences; Department of Clinical Laboratory, the Third Affiliated Hospital of Southern Medical University, Southern Medical University, Guangzhou, China.

Communications biology
|July 29, 2024
PubMed
概括

奥尔法托美丁4 (OLFM4) 调节3组先天性淋巴细胞 (ILC3s) 和IL-22的产生,影响肠道炎症. 缺少OLFM4会损害ILC3的功能,增加对感染的易感性和对结肠炎的抗性.

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