在门诊结肠外科手术患者回家后的无阿片类药物止痛:单中心观察性研究
Marilyn Gosgnach1,2, Philippe Chasserant3,4, Mathieu Raux5,6
1Department of Anesthesia and Intensive Care, Hôpital Privé de l'Estuaire, 505 rue Irene Joliot Curie, Le Havre, 76620, France. marilyn.gosgnach@wanadoo.fr.
BMC anesthesiology
|July 29, 2024
概括
这项研究表明,非阿片类药物疼痛管理有效控制了腹腔镜切除术后的疼痛. 这种方法可以避免在接受门诊手术的患者中出现阿片类药物副作用.
科学领域:
- 麻醉学和疼痛管理
- 结肠直肠手术 结肠直肠手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 基于阿片类药物的止痛药具有风险,促使人们对门诊手术的非阿片类药物替代品产生兴趣.
- 在出院后确保足够的疼痛缓解是无阿片类药物策略的一个关键问题.
- 这项研究研究了对门诊腹腔镜切除术患者的无阿片类药物治疗方法.
研究的目的:
- 评估无阿片类药物止痛策略的疗效.
- 为了确定非阿片类药物是否可以在门诊腹腔镜切除术后提供令人满意的疼痛控制.
- 评估在没有阿片类药物治疗的患者中中度至严重疼痛的发生率.
主要方法:
- 一项对144名接受门诊腹腔镜切除术的患者进行的回顾性观察性研究.
- 手术后的疼痛缓解是使用青和nefopam进行的.
- 在动员时使用数值评分表 (NRS) 评估疼痛;其他结果包括血液动力学稳定性,温度和炎症标志物.
主要成果:
- 在术后第一天中度至重度疼痛 (NRS>4) 的发生率为19% (95% CI,0.13-0.27).
- 手术后的疼痛水平随着时间的推移显著下降.
- 患者人口统计包括大多数男性 (平均年龄59岁),ASA分数为1,2或3.
结论:
- 非阿片类药物止痛药,使用青和尼福帕姆,似乎有效管理在门诊腹腔镜切除术后的疼痛.
- 这种无阿片类药物策略成功地避免了与阿片类药物使用相关的不良影响.
- 这些发现支持使用非阿片类药物治疗方案,以改善患者的康复和安全.
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