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在金沙萨 (刚果民主共和国) 的儿童中与艾滋病相关的认知障碍
Esther Maboso Ekolo1,2,3,4, Aimée Masaya Mupuala5,6,7, Joseph Mabiala Bodi5,8
1Department of Paediatrics, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo. stherekolo@gmail.com.
BMC public health
|July 29, 2024
概括
与健康同龄人相比,感染艾滋病毒的儿童经历了显著的认知缺陷,影响了语言,非语言和空间能力. 早期识别和管理这些神经认知障碍对于改善生活质量至关重要.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
背景情况:
- 人类免疫缺陷病毒 (HIV) 感染增加了神经认知障碍的风险.
- 抗逆转录病毒治疗可能无法完全预防与艾滋病毒相关的免疫激活和神经损伤.
- 关于艾滋病毒在该国年轻人群中的认知影响的数据有限.
研究的目的:
- 为了比较艾滋病毒阳性儿童与健康儿童的认知表现.
- 评估儿童艾滋病毒感染的认知缺陷的患病率和性质.
主要方法:
- 从2020年11月到2021年3月进行了一项比较的横截面研究.
- 参与的216名儿童 (106名艾滋病毒阳性,108名健康) 年龄在6至15岁之间.
- 认知能力使用差异能力量表第二版 (DAS-II) 进行评估.
主要成果:
- 与对照组相比,艾滋病毒感染儿童在口头,非口头,空间和一般概念能力方面的得分明显较低.
- 超过一半的HIV阳性参与者表现出认知障碍.
- 对照组的孩子在诊断测试和学校成绩上取得了更高的成绩.
结论:
- 认知障碍是艾滋病毒阳性儿童中普遍存在的并发症,影响了研究小组中的50%以上.
- 这些缺陷对生存,生活质量和日常功能有重大影响.
- 临床识别和管理儿童艾滋病毒认知缺陷是必不可少的.
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