在有色皮肤的炎症后超色素的治疗:一个系统的审查
Kristie Mar1, Bushra Khalid1, Mahan Maazi1
1Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Journal of cutaneous medicine and surgery
|July 30, 2024
概括
后炎性多色素 (PIH) 是一种慢性皮肤疾病,不成比例地影响着肤色较深的人. 这次审查发现治疗疗效有限,激光疗法在某些情况下显示最有希望的完全解决方案.
科学领域:
- 皮肤病学 皮肤病学
- 审美医学是一种美学医学.
- 基于证据的医学基于证据的医学.
背景情况:
- 后炎性多色素 (PIH) 是一种常见的皮肤病问题,尤其在肤色较深的人群中普遍存在.
- PIH呈现出慢性过程,并且经常证明有效治疗具有挑战性.
- 本系统性审查的重点是总结PIH的治疗结果,特别强调皮肤颜色 (SOC) 种群.
研究的目的:
- 系统地审查和总结后炎性色素增多 (PIH) 的治疗结果.
- 专门分析皮肤有色 (SOC) 个体的治疗疗效.
- 确定最有效的干预措施和未来研究领域,以对风险人群进行PIH管理.
主要方法:
- 在主要数据库 (MEDLINE,Embase,PubMed,Cochrane) 进行了全面的文献搜索.
- 搜索遵循了系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 分析了48项涉及1356名SOC个体的研究数据.
主要成果:
- 局部视网类药物和激光治疗是PIH最常见的干预措施.
- 在接受局部视网体治疗的85%的参与者和接受激光治疗的66%的参与者中观察到部分改善.
- 激光疗法在26%的患者中实现了完全康复,尽管也报告了PIH恶化. 其他治疗方法,如化学剥皮和化,表现不那么有效.
结论:
- 后炎性多色素 (PIH) 是一种持续的问题,严重影响着肤色较深的人.
- 目前的治疗方法表明,对于PIH,缺乏全面的强大疗效.
- 在风险人群中,对PIH进行改进和更有效的干预措施有很大需要.
相关概念视频
01:19Pigmentation
2.3K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.3K
01:30Skin Cancer
4.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.0K
01:14Changes in Skin Color: Clinical Perspectives
1.9K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.9K
01:22Burn Injuries
2.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
2.4K