静脉流动和心脏大小,形状和心室收缩性在胎儿的估计体重小于10th百分点的胎儿
Manesha Putra1, Emma Elizabeth Helen Peek1, Greggory R Devore2,3,4
1University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
概括
静脉流量 (UVF) 测量显著改善了胎儿生长限制 (FGR) 和小至妊娠年龄 (SGA) 的胎儿心脏异常的检测. 这种加强的监测可以更好地识别患有心血管问题的胎儿.
科学领域:
- 周围生理学 周围生理学
- 胎儿心脏病学 胎儿心脏病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 胎儿生长限制 (FGR) 和小于妊娠年龄 (SGA) 的胎儿表现出心脏功能障碍的风险增加.
- 标准多普勒监测可能无法完全捕捉这些高风险人群中心脏异常的频谱.
研究的目的:
- 为了比较胎儿心脏异常,估计胎儿体重 (EFWs) <10百分位,区分FGR和SGA.
- 评估静脉流量 (UVF) 测量与标准多普勒监测相比在检测心脏功能异常方面的有用性.
主要方法:
- 对95名胎儿进行前性观察队列研究,EFW<10百分位.
- 评估胎儿心脏的大小,形状和心室收缩率,使用各种心声回声学参数.
- 将UVF测量与标准多普勒测量 (动脉,中脑动脉,心肺复苏) 进行比较,以预测心脏功能异常.
主要成果:
- 与对照组相比,心脏大小,形状和收缩率的异常在EFW<10百分点的胎儿中显著增加.
- 在FGR和SGA胎儿之间没有观察到心脏异常的显著差异.
- 与动脉多普勒 (17.2%) 相比,UVF在76名患者的子组中发现了明显更多患有收缩异常的胎儿 (37.9%).
结论:
- 将UVF测量添加到监测协议中,使心室收缩异常的检测率翻了一番.
- 建议对FGR和SGA胎儿进行UVF评估,以更好地分层低氧症的严重程度,并识别那些未来心血管功能障碍风险较高的人.
相关概念视频
Fetal Circulation
891
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
891
Development of Blood Vessels
555
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
555
Blood Flow
69.5K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
69.5K
Development of the Heart
906
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
906
Coronary Circulation
2.5K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
2.5K


