燃烧口腔综合征中的认知特征与轻度认知障碍:一项比较研究
Grazia Daniela Femminella1, Federica Canfora2, Gennaro Musella2,3
1Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Oral diseases
|July 30, 2024
概括
与老年患者 (G-MCI) 相比,患有燃烧口腔综合征 (BMS-MCI) 的患者表现出更多的认知和心理缺陷,包括抑郁和焦虑. 这些发现强调了针对轻度认知障碍 (MCI) 进行量身定制治疗的必要性.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 老年学是一门学科.
背景情况:
- 燃烧口腔综合征 (BMS) 越来越多地被认为可能与神经和心理因素有关.
- 轻度认知障碍 (MCI) 影响着老年人口的很大一部分,其潜在原因各不相同.
- 了解不同MCI亚型的不同认知和心理特征对于有针对性的干预至关重要.
研究的目的:
- 为了比较患有BMS-MCI的患者和患有G-MCI的老年患者之间的认知和心理方面.
- 确定潜在的认知衰退预测因素,包括疼痛,情绪障碍,生物标志物和与年龄相关的白质变化 (ARWMCs).
- 阐明与BMS-MCI相关的特定认知缺陷.
主要方法:
- 招募了40名BMS-MCI和40名G-MCI患者的队列,并根据年龄,性别和教育程度进行了匹配.
- 综合性评估包括心理评估,睡眠度量表和一系列认知测试 (MMSE,TMT,Corsi,RAVLT等). ) 的情况.
- 分析的重点是比较各组之间的表现,并将发现与潜在的影响因素相关联.
主要成果:
- 老年MCI患者在部区域表现出显著更高的ARWMCs.
- 患有BMS-MCI的患者表现出较高的抑郁和焦虑水平,以及较低的迷你精神状态检查 (MMSE) 成绩.
- 患有BMS-MCI的患者在处理速度和执行功能方面表现出更大的损害,由更高的Trail Making Test-A (TMT-A) 得分证明.
结论:
- BMS-MCI的特点在于在全球认知和处理速度方面存在明显的缺陷.
- 教育,疼痛,胆固醇,睡眠和焦虑等因素显著影响MCI的认知评估.
- 针对认知和情绪领域的个性化治疗策略对于BMS患者的MCI管理至关重要.
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