在患有冠心病的糖尿病患者中,Gensini评分的相关性分析
Jinyue Qi1,2,3,4, Yunzhe Wang1,2,3,4, Zhiyu Liu1,2,3,4
1Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, 450052 Zhengzhou, Henan, China.
Reviews in cardiovascular medicine
|July 30, 2024
概括
高甘西尼分数表明糖尿病 (DM) 和冠状动脉心脏病 (CHD) 患者心脏和脑血管重大不良事件 (MACCE) 的风险增加. 这一发现有助于预测这些高风险个体的不良结果.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 评估风险因素对于管理糖尿病 (DM) 和冠心病 (CHD) 患者至关重要.
- 根西尼评分 (Gensini score) 是一种用来量化冠状动脉狭窄症严重性的工具.
研究的目的:
- 调查甘西尼分数与重大心脏和脑血管不良事件 (MACCEs) 的发生率之间的相关性.
- 评估Gensini得分对DM和CHD患者MACCE的预测价值.
主要方法:
- 纳入了802名患有DM和CHD的患者,随访时间中位数为3000天.
- 使用接收器操作特征 (ROC) 曲线来确定最佳的根西尼分数切线来预测MACCEs.
- 单变量和多变量考克斯回归和卡普兰-梅尔分析确定了风险因素,并比较了各组之间的MACCE发病率.
主要成果:
- 根西尼分数显示曲线下的面积 (AUC) 为0.675,用于预测MACCEs.
- 根西尼分数切线为74.8605,产生了68.8%的灵敏度和56%的特异性.
- 较高的甘西尼分数与较高的MACCE发病率显著相关.
结论:
- 高根西尼分数是DM和CHD患者中MACCE的重要危险因素.
- 根西尼评分可以帮助识别患有心脏和脑血管不良事件风险较高的患者.
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