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增强内皮形成殖民地细胞用于治疗糖尿病血管并发症:挑战和临床前景

Yaqiong Liu1, Caomhán J Lyons1, Christine Ayu1

  • 1Regenerative Medicine Institute (REMEDI), Biomedical Sciences Building, University of Galway, Galway, Ireland.

Frontiers in endocrinology
|July 30, 2024
PubMed
概括

内皮殖民地形成细胞 (ECFC) 显示出治疗糖尿病血管并发症的前景. 然而,糖尿病会损害ECFC的功能,需要制定策略来增强它们对患者的治疗潜力.

关键词:
临床翻译 临床翻译在糖尿病中,糖尿病是血糖类的.与疾病相关的细胞功能障碍内皮细胞是形成殖民地的细胞.遗传修饰是一种基因改造.药理学调节 药理学调节

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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