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中期结果比较隔离先天性静脉隔膜缺陷的外科修复与腹腔器械关闭的中期结果:系统审查和元分析

Juemin Yu^1,2, Rong Liufu³, Ximeng Wang⁴

¹School of Medicine, South China University of Technology, 510641 Guangzhou, Guangdong, China.

Reviews in cardiovascular medicine

|July 30, 2024

概括

对于VSD而言,心室周围装置关闭 (PDC) 是安全有效的,提供较少的外科创伤. 然而,传统的手术修复 (CSR) 显示出更高的成功率,而PDC可能会导致更多的残留分流和大动脉吐问题.

科学领域:

心脏病学心脏病学
心血管外科心血管外科
医疗器械医疗器械

背景情况:

室腔隔膜缺陷 (VSD) 是一种常见的先天性心脏异常.
透心器装置关闭 (PDC) 和传统的手术修复 (CSR) 是VSD的治疗选择.
这两种VSD治疗方法的中期结果需要进行比较分析.

研究的目的:

为了比较心室周围器件关闭 (PDC) 与心室隔膜缺陷 (VSD) 常规手术修复 (CSR) 的中期结果.
在VSD患者中评估PDC与CSR相比的疗效和安全性.

主要方法:

2005年1月1日至2020年10月15日期间发表的研究的系统审查和元分析.
搜索了PubMed,Cochrane图书馆和Web of Science数据库的英语或中文语言研究.
分析了使用frequentist元分析的中期结果,以风险比率 (RR) 和95%置信区间 (CI) 进行分析.

主要成果:

包括15项与4381名患者进行的研究 (PDC=2016,CSR=2365).
传统的手术修复 (CSR) 证明了更高的成功率 (RR,0.97;P=0.001).
周心器装置关闭 (PDC) 显示出更多的残留分流 (RR,9.07;P<0.001),而CSR则有更多的大动脉吐 (RR,1.59;P=0.03). 在轻微或严重的并发症中没有发现显著差异.

结论:

透心器装置关闭 (PDC) 是一种安全有效的VSD治疗方法,可以减少手术损伤和更短的住院时间.
大动脉反是一种潜在的担忧,需要在PDC后的随访期间进行监测.
传统的手术修复 (CSR) 可能为VSD关闭提供更高的成功率.

关键词:

一大动脉的反.传统的外科手术修复.这是一个元分析.透心器装置的闭合方式腹腔隔膜缺陷腹腔隔膜缺陷

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