营养不良及其对老年患者败血症结果的影响
Muhammad Daud1, Fahim Ullah1, Muhammad Uzair1
1General Surgery, Lady Reading Hospital, Peshawar, PAK.
Cureus
|July 30, 2024
概括
营养不良显著恶化了老年败血症患者的住院结果,增加了ICU入院,死亡率和再入院. 早期的营养支持对于改善患者康复和生存率至关重要.
科学领域:
- 老年病的医生 老年病的医生
- 传染性疾病 传染性疾病
- 营养科学 营养科学
背景情况:
- 营养不良在老年人中很普遍,影响住院的结果,特别是在严重的疾病中,如败血症.
- 与年龄相关的生理变化和并发症加剧了与老年人营养不良相关的风险.
研究的目的:
- 调查营养不良对感染败血症的老年人住院结果的影响.
- 确定与这种脆弱人群中的营养不良相关的特定不良结果.
主要方法:
- 进行了一项前性队列研究,涉及390名老年败血症患者 (≥55岁).
- 收集的数据包括临床病史,并发症,营养状况,ICU入院,机械呼吸,死亡率和30天再入院.
- 进行了统计分析,包括多变量分析,以评估营养状况和结果之间的关系.
主要成果:
- 营养不良患者的ICU入院率 (52.82%对29.23%),机械呼吸 (45.13%对16.41%),死亡率 (27.18%对14.87%) 和30天再入院率 (28.21%对12.82%) 显着更高.
- 营养不良的个体经历了更长的住院时间 (18.1天 vs 12.6天).
- 营养不良被确定为长时间住院 (β = 2.8,p < 0.001) 和增加死亡风险 (OR = 3.2,95% CI: 1.9-5.4,p < 0.001) 的重要预测因素.
结论:
- 营养不良是一个关键因素,显著恶化了老年败血症患者住院的结果.
- 这些发现强调,迫切需要在患有败血症的老年人中进行主动营养评估和干预,以减轻不良结果.
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