急性心脏病综合征:流行病学,病理生理学,评估和治疗
1Department of Cardiology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730 Beijing, China.
Reviews in cardiovascular medicine
|July 30, 2024
概括
在急性损伤 (AKI) 患者中,急性心脏综合征 (CRS) 与不良结果有关. 本综述涵盖了AKI中CRS流行病学,病理生理学和治疗挑战.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 密集护理医学 密集护理医学
背景情况:
- 急性心综合征 (CRS) 是心脏重症监护病房中常见的并发症,特别是在急性损伤 (AKI) 患者中.
- CRS与预后明显差相关.
- 目前的理解表明卷入体积失调,神经激素激活和交感神经系统过度活跃.
研究的目的:
- 审查AKI患者急性CRS的流行病学.
- 探索急性CRS的潜在病理生理学.
- 讨论AKI中急性CRS的临床评估和当前治疗策略.
主要方法:
- 关于急性心综合征现有研究的文献综述.
- 与CRS和AKI相关的流行病学数据的分析.
- 综合有关病理生理机制,临床表现和治疗干预措施的信息.
主要成果:
- 急性CRS经常在心脏重症监护机构内观察到AKI患者.
- 一些因素,包括体积状态,氨酸- ангиотензин- алдостерон系统和神经激素激活,都与CRS的发展有关.
- 在鉴定急性CRS中功能变化的可靠生物标志物方面存在重大差距.
- 在AKI中急性CRS的基于证据的治疗选择仍然有限.
结论:
- 在AKI中,急性CRS具有复杂的临床挑战,诊断工具和治疗选择有限.
- 需要进一步的研究来确定预测生物标志物,并开发有效的基于证据的治疗方法.
- 对CRS病理生理学的全面理解对于改善重症监护机构患者的治疗结果至关重要.
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