青少年和年轻成人高血压的心血管影响
Rupesh Raina1,2, Amrit Khooblall1, Raghav Shah1
1Akron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, OH 44307, USA.
Reviews in cardiovascular medicine
|July 30, 2024
概括
儿科高血压影响4%的儿童,与早期心血管变化有关,如左心室质量指数增加和大动脉硬. 早期诊断和治疗对于长期的心脏健康至关重要.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 儿科高血压是一种严重的健康问题,影响美国约3.5%的儿童和青少年.
- 它对心血管系统产生不利影响,可通过左心室质量指数 (LVMI),左心室缩 (LVH),心动脉内膜介质厚度 (cIMT) 和大动脉硬度来衡量.
- 多种潜在的病因导致儿科高血压,包括脏疾病,先天性疾病,内分泌疾病,睡眠呼吸暂停和某些药物.
研究的目的:
- 综合目前关于儿科高血压的临床数据.
- 分析儿童和青少年高血压的患病率和心血管影响.
- 突出儿童高血压的早期检测和管理的重要性.
主要方法:
- 对儿科高血压的临床数据进行了广泛的文献搜索.
- 分析包括了67篇文章,涵盖了来自189,477名受试者的数据.
- 提取的数据集中在高血压发生率,LVMI,LVH,cIMT和大动脉硬.
主要成果:
- 从1994年到2018年,儿科高血压 (年龄<18岁) 的平均患病率为4%.
- 与对照组相比,高血压儿童的平均LVMI (39.3g/m2) 和cIMT (0.55mm) 均高于对照组 (30.1g/m2和0.49mm).
- 与正常血压患者相比,高血压患者在门诊动脉硬度参数中显著增加了SBP,DBP,MAP和PP.
结论:
- 儿科高血压与心血管疾病的早期症状有关,其证据是高的LVMI,LVH,cIMT和动脉硬.
- 非侵入性措施证实高血压儿童的目标器官损伤.
- 儿童群体高血压的及时诊断和治疗对于预防长期心血管疾病和死亡率至关重要.
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