营养状况对COVID-19引起的嗅觉功能障碍的影响
Elizabeth M Mastoloni1, Evan French1, Daniel H Coelho1
1Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University School of Medicine, Richmond, Virginia, U.S.A.
The Laryngoscope
|July 30, 2024
概括
营养不良影响COVID-19嗅觉功能障碍的风险. 过度营养会增加这种风险,而营养不良可能会对感染后的嗅觉丧失提供轻微的保护.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 营养科学 营养科学
背景情况:
- 嗅觉功能障碍是COVID-19的一个常见症状.
- 了解COVID-19引起的化学感官功能障碍的易感性因素至关重要.
研究的目的:
- 调查营养不良 (营养不良和营养过剩) 与患COVID-19相关化学感官功能障碍的风险之间的联系.
主要方法:
- 利用N3C数据库识别COVID-19和化学感官功能障碍的成年人.
- 分析了先前存在的营养不良或营养过剩的诊断.
- 计算的几率比率来评估与营养状况相关的嗅觉功能障碍的风险.
主要成果:
- 过度营养与嗅觉功能障碍的风险更高有关 (OR 1.419,p<0.0001).
- 营养不良表明嗅觉功能障碍的风险降低 (OR 0.731,p<0.0001).
- 嗅觉功能障碍的患病率在过度营养的COVID-19患者中为0.66%,在营养不良的COVID-19患者中为0.36%.
结论:
- 过度营养可能会增加COVID-19感染后发生嗅觉功能障碍的风险.
- 营养不良可能会对与COVID-19相关的气味丧失产生保护作用.
- 需要对代谢和炎症因素进行进一步的研究.
相关概念视频
Physiology of Smell and Olfactory Pathway
8.2K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
8.2K
Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K
Overview of Carbohydrate Metabolism
845
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
845
COPD: Pathogenesis and Clinical Features
251
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
251
Acute Respiratory Failure-V
126
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
126
Taste Buds and Receptors
1.9K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
1.9K


