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在幼儿中查自闭症谱系障碍:仍然没有足够的证据
Bogdan Grigore1, Jaime Peters1, Jessica Williams1
1University of Exeter, Exeter, UK.
Journal of primary care & community health
|July 30, 2024
概括
早期发现自闭症谱系障碍 (ASD) 是有希望的,但目前关于幼儿查工具和干预措施的证据是不确定的. 需要更严格的研究来确认益处并提高诊断准确度.
科学领域:
- 发育儿科 发育儿科
- 儿童心理学 儿童心理学
- 神经发育障碍 神经发育障碍
背景情况:
- 早期发现自闭症谱系障碍 (ASD) 可以减轻其影响.
- 以前的审查表明,支持幼儿ASD查计划的证据有限.
研究的目的:
- 更新有关幼儿自闭症诊断稳定的证据.
- 评估幼儿自闭症查工具的准确性.
- 评估早期干预对被查发现患有自闭症的幼儿的好处.
主要方法:
- 对33项研究进行了系统审查.
- 对诊断稳定性,查工具准确性 (包括M-CHAT版本) 和早期干预结果的分析.
- 评估研究偏差,包括失明,样本大小和随访持续时间.
主要成果:
- 诊断稳定性估计有所不同 (71.9%-100%),大多数研究的随访时间很短,偏差风险很高.
- 来自25项研究的查工具准确性数据显示了可变的灵敏度 (0.67-1.0),通常具有高偏差风险.
- 有限的证据表明,早期干预对被查的儿童有显著的改善.
结论:
- 目前关于自闭症查,诊断稳定性和幼儿早期干预措施的证据尚未确定.
- 未来的研究需要盲目的诊断评估,更长的随访期,并减少磨损以提高可靠性.
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