达利尔病中阿西特雷丁诱导的原发性甲状腺功能低下症:一个罕见的病例报告
Betsy Susan Babu1, Carol Z Fernandes2, Balachandra Bhat3
1Department of Pharmacy Practice, Karnataka College of Pharmacy, Bengaluru, Karnataka, India.
Indian journal of pharmacology
|July 30, 2024
概括
用于达里尔病的阿西特雷丁很少会导致甲状腺功能低下症. 这一案例凸显了由于潜在的不良影响,在阿西特雷丁治疗期间需要进行一致的血液监测.
科学领域:
- 皮肤病学 皮肤病学
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 阿西特雷丁是一种用于达里尔病 (DD) 的第二代视网.
- 它通过与核受体结合而起作用,改变基因表达.
- 甲状腺功能低下是阿西特雷丁治疗的一个不寻常的副作用.
研究的目的:
- 报告一种罕见的阿西特雷丁诱导的甲状腺功能低下症病例,该病患者患有达利尔病.
- 强调在阿西特雷丁治疗期间监测不良反应的重要性.
主要方法:
- 一个41岁的男性患者的病例报告,他患有达里尔病.
- 在阿西特雷丁治疗前和治疗期间监测常规血液检查.
- 用甲状腺素治疗诱导的甲状腺功能低下症.
主要成果:
- 患者在阿西特雷丁治疗后出现了甲状腺功能低下症.
- 甲状腺素有效地治疗了阿西特雷丁诱导的甲状腺功能低下症.
- 由于副作用,阿西特雷丁治疗被 discontinued,患者继续局部治疗.
结论:
- 阿西特雷丁可以导致甲状腺功能低下,即使在没有先前并发症的患者中也是如此.
- 在阿西特雷丁治疗期间,持续的血液监测至关重要,以检测副作用.
- 这一案例强调了对罕见的药物诱导副作用的警的重要性.
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