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Updated: Jun 18, 2025

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
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Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

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通过α-hemolysin探索ssDNA转位,使用粗粒度引导分子动力学

Cagla Okyay1, Delphine Dessaux1, Rosa Ramirez1

  • 1Université Paris-Saclay, Univ Evry, CY Cergy Paris Université, CNRS, LAMBE, 91025, Évry-Courcouronnes, France. nathalie.basdevant@univ-evry.fr.

Nanoscale
|July 30, 2024
PubMed
概括

粗粒度分子动力学模拟揭示了通过蛋白质纳米孔影响单链DNA (ssDNA) 转位的关键因素. DNA 的电荷和方向显著影响转移速度和动态,为实验观测提供了洞察力.

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