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Updated: Jun 20, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

一种真核转录激活剂,具有 prokaryotic 抑制剂的 DNA 特异性

R Brent, M Ptashne

    Cell
    |December 1, 1985
    PubMed
    概括

    研究人员创造了一种混合蛋白,LexA-GAL4,它结合DNA并激活酵母中的基因转录. 这表明,一个 prokaryotic DNA 结合域可以取代酵母,同时保持转录激活.

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