减少2型糖尿病成年人久坐行为的干预措施:系统性审查和元分析
Siobhan Smith1,2, Babac Salmani1, Jordan LeSarge2
1Department of Kinesiology, Faculty of Health Sciences, Western University, London, Ontario, Canada.
PloS one
|July 30, 2024
概括
减少静坐时间显著改善了2型糖尿病 (T2D) 的成年人血糖的控制. 打破长时间坐的干预措施对心脏代谢生物标志物有好处,这表明一种可持续的行为改变方法.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 行为科学 行为科学
背景情况:
- 2型糖尿病 (T2D) 管理传统上涉及体力活动,营养和药物治疗.
- 新出现的证据强调了久坐不动行为对心脏代谢健康的有害影响.
- 减少和中断长时间的坐着时间越来越被认为是T2D管理的关键.
研究的目的:
- 系统地审查和综合旨在减少和/或打破久坐行为的干预措施的有效性.
- 评估这些干预措施对T2D成人心脏代谢生物标志物的影响.
- 评估这种人群中静坐行为修改的可行性和可持续性.
主要方法:
- 在多个科学数据库 (PubMed,EMBASE,Scopus等) 中进行了全面的数据库搜索. 从2022年9月到2024年1月.
- 该审查遵循PRISMA指南,并使用Cochrane风险偏差工具评估研究质量.
- 包括28篇文章,对短期和长期干预数据进行了元分析.
主要成果:
- 短期干预 (<4天) 显著改善了24小时连续间歇性葡萄糖 (SMD: -0.819,p<0.001) 和食后间歇性葡萄糖 (SMD: -0.347,p=0.004).
- 长期干预 (5周-3年) 在11项研究中,在10项研究中,表现出了对久坐行为措施的改善.
- 在八个长期干预中,有八个报告至少一个心脏代谢生物标志物的改善.
结论:
- 减少久坐不动的行为,独立于结构化的体力活动,可以有效地改善T2D成年人的血糖控制.
- 针对久坐行为的干预措施有望提高T2D中的心脏代谢健康.
- 久坐不动的行为修改代表了一种潜在的可行和可持续的策略来管理2型糖尿病.
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