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相关概念视频

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

10.9K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
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Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

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The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
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相关实验视频

Updated: Jun 18, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
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Isolation of Human Islets from Partially Pancreatectomized Patients

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并非所有的症都是1型 - - 请记住,Flatbush是1型的.

Sarah Craus1,2, Abigail Mula1,2, David Coppini2,3,4

  • 1Department of Medicine, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

British journal of hospital medicine (London, England : 2005)
|July 30, 2024
PubMed
概括

一名35岁的男子出现了无法控制的糖尿病症状,包括过度口渴和排尿,以及显著的体重减轻. 他的高HbA1c和血糖证实了新发型2型糖尿病 (T2DM).

关键词:
不典型的糖尿病是什么?自动抗体是一种自身抗体.糖尿病酸性酸性容易发生症的糖尿病.

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Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
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Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets

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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

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Isolation of Human Islets from Partially Pancreatectomized Patients
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Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
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Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets

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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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科学领域:

  • 内分泌学 在内分泌学.
  • 代谢障碍 代谢障碍 代谢障碍
  • 临床案例研究临床案例研究

背景情况:

  • 2型糖尿病 (T2DM) 是一个日益严重的全球健康问题.
  • 早期诊断和管理对于预防并发症至关重要.

研究的目的:

  • 在年轻成年人中呈现一种新发型T2DM病例.
  • 突出临床表现和初步诊断发现.

主要方法:

  • 一个35岁的男性患者的病例报告.
  • 临床检查,包括对多尿症和多多的评估.
  • 实验室调查:HbA1c,血糖,水平,尿液分析和代谢面板.

主要成果:

  • 患者出现了严重的高血糖症 (HbA1c 119 mmol/mol,血糖为 22.84 mmol/L).
  • 症状包括多尿症,多滴水症和5公斤的体重减轻.
  • 阳性子和葡萄糖uria被发现,与轻度代谢酸化.

结论:

  • 这一案例强调了在出现经典高血糖症状的年轻成年人中考虑T2DM的重要性.
  • 及时诊断和干预对于管理T2DM及其急性并发症至关重要.