在50-64岁的人群中,限制性螺旋测量模式和保存比率导致螺旋测量受损
Kjell Torén1,2, Anders Blomberg3, Linus Schiöler1
1Occupational and Environmental Medicine, School of Public Health and Community Medicine.
Annals of the American Thoracic Society
|July 30, 2024
概括
限制性螺旋测量模式 (RSP) 和保留比率受损螺旋测量 (PRISm) 影响了总人口的5.1%. 这两种情况都有共同的心血管和代谢特征,但肺气与PRISm有独特的联系.
科学领域:
- 肺部医学 肺部医学
- 诊断成像 诊断成像 诊断成像
- 流行病学 流行病学
背景情况:
- 在一般人群中,限制性螺旋测量模式 (RSP) 和保留比率受损螺旋测量 (PRISm) 的患病率和特征尚不清楚.
- 支气管扩展后的螺旋测量和肺部的计算机断层扫描 (CT) 对于理解这些模式至关重要.
研究的目的:
- 调查RSP和PRISM的共同和独特特征.
- 为了确定RSP和PRISm在一般人口样本中的患病率.
主要方法:
- 利用了来自瑞典心肺生物图像研究 (SCAPIS) 的数据,其中28555名50-64岁的参与者.
- 通过问卷,肺部CT,支气管扩展器后螺旋计和冠状动脉化 (CAC) 评分来评估参与者.
- 员工调整后勤回归来计算赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- RSP和PRISm的患病率均为5.1%,在从未吸烟者中也有类似的比例.
- 共同特征包括目前的吸烟,呼吸不全,慢性支气管炎,类风湿性疾病,糖尿病,缺血性心脏病,支气管壁加厚,间歇性肺异常和支气管切除.
- 肺是与PRISm唯一相关的 (OR,1.69;95%CI,1.36-2.10),而CAC得分≥300与PRISm有关.
结论:
- PRISM和RSP具有共同的呼吸,心血管和代谢条件.
- 肺是与PRISM相关的,而不是RSP.
- 冠状动脉样硬化可能与PRISm有关,这表明潜在的共享途径.
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