在人类骨髓中发现和分析微塑料
Xiaoli Guo1, Lin Wang2, Xiaoyang Wang3
1Henan Office for Cancer Control and Research, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital. Henan International Joint Laboratory of Cancer Prevention, Henan Engineering Research Center of Cancer Prevention and Control, 450008 Zhengzhou, Henan, China; College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Journal of hazardous materials
|July 30, 2024
概括
微塑料 (MPs) 存在于人类骨髓中,在所有分析的样本中检测到. 这项突破性的研究确定了五种聚合物类型,聚乙烯是最常见的,并揭示了大多数MP都在100微米以下.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 人类健康 人类健康 人类健康
背景情况:
- 人类暴露于微塑料 (MPs) 是一个越来越令人担忧的问题.
- 在各种人体器官中发现了MPs,但缺乏骨髓数据.
- 了解骨髓中MP的存在对于评估健康风险至关重要.
研究的目的:
- 在人类骨髓样本中检测和量化微塑料 (MPs).
- 描述骨髓中MPs的大小,形态和聚合物类型.
- 为了首次确定MPs在人类骨髓中的存在.
主要方法:
- 热解气体染色学-质谱学 (Py-GC/MS) 用于MP度.
- 激光直接红外光谱 (LD-IR) 和扫描电子显微镜 (SEM) 用于表征.
- 对16个人类骨髓样本的分析.
主要成果:
- 在所有16个骨髓样本中检测到微塑料 (MP) (平均度:51.29μg/g).
- 确定了五种聚合物类型:聚乙烯 (PE),聚烯 (PS),聚乙烯 (PVC),聚胺66 (PA66) 和聚烯 (PP).
- PE最常见 (93.75%的检测),而PS的检测率为100%;89.82%的MP是<100微米.
结论:
- 这项研究提供了人类骨髓中微塑料 (MP) 存在的第一个证据.
- 这些发现突出了对造血系统的潜在毒理影响.
- 需要进一步的研究来了解MP机制和骨髓对健康的影响.
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