长期阅读的蛋白质基因组学将与疾病相关的sQTL与疾病的蛋白质异型因子连接起来

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Updated: Jun 18, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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Abdullah Abood1, Larry D Mesner2, Erin D Jeffery3

  • 1Center for Public Health Genomics, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

American journal of human genetics
|July 30, 2024
PubMed
概括

这项研究使用长读测序将遗传变异与特定蛋白质异型联系起来,揭示了遗传关联如何影响蛋白质多样性和功能,特别是在骨密度调节方面.

关键词:
在GWAS中,GWAS就是GWAS.这就是PacBio.这就是为什么TPM2是TPM2.替代性拼接是一种替代性的拼接.骨矿物质密度 骨矿物质密度长时间读取RNA-seqq.这种lrRNA-seqq.骨质母细胞的骨质母细胞.蛋白质的异形蛋白质.蛋白质基因组学拼接定量特征的位置.

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