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睡眠时间短和肥胖之间的关系中的性别差异:系统性审查和元分析
Maria G Lange1, Christodoulos Neophytou2, Francesco P Cappuccio3
1Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK; Warwickshire Institute for the Study of Diabetes Endocrinology and Metabolism, University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK.
概括
短暂的睡眠时间增加男性和女性的肥胖风险. 这次元分析发现,与睡眠时间相关的性别之间的肥胖风险没有显著差异,这表明对男性和女性的影响类似.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 睡眠医学 睡眠医学
背景情况:
- 肥胖是全球主要的健康问题,对发病率和死亡率做出了重大贡献.
- 睡眠时间短暂是肥胖的已知危险因素,但其对男性和女性的影响差异尚未得到充分证实.
研究的目的:
- 系统地评估和比较短睡眠时间和男性与女性肥胖发病率之间的关联.
主要方法:
- 进行了对纵向队列研究 (至少12个月的观察) 的元分析,搜索了Medline,Embase和Web of Science数据库.
- 研究的质量使用纽卡斯尔-太华尺度来评估. 数据使用随机效应模型进行了聚合,计算了几率比率 (ROR) 的比率,以比较性别之间的效应大小.
- 进行了敏感性分析和异质性评估 (I2统计).
主要成果:
- 六项研究,包括4582篇获取文章,符合纳入标准.
- 睡眠时间短暂与男性 (OR 1.26,95% CI 1.13-1.40) 和女性 (OR 1.36,95% CI 1.16-1.59) 的肥胖发病率增加有显著关联.
- 睡眠时间短和肥胖发生率之间的关联在性别之间没有显著差异 (ROR 1.04,95% CI 0.79-1.36).
结论:
- 报告睡眠时间短的男性和女性都有类似的肥胖风险.
- 这些发现表明,针对睡眠时间的干预措施可能对预防两性肥胖同样重要.
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