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中国内脏脂肪指数的线性关联及其与高尿血的变化:一项前性队列研究

Jia Chen¹, Xuejiao Liu², Shuai Lu³

¹Department of Endocrinology, Beijing Jishuitan Hospital, Capital Medical University, 100035 Beijing, China.

Nutrition, metabolism, and cardiovascular diseases : NMCD

|July 30, 2024

概括

中国内脏脂肪指数 (CVAI) 与患上高尿素血症 (HUA) 的风险更高有关. 较高的CVAI水平和随着时间的推移而增加的CVAI预测了事件HUA,这表明它在风险识别中的实用性.

科学领域:

代谢健康代谢健康
肥胖问题研究研究
流行病学流行病学

背景情况:

超尿血症 (HUA) 是一种与各种健康问题相关的代谢状况.
越来越多地认为内脏脂肪是代谢障碍的一个关键因素.
中国内脏脂肪指数 (CVAI) 是评估内脏脂肪的新型指标.

研究的目的:

调查中国内脏脂肪指数 (CVAI) 与高尿素血 (HUA) 发生率之间的关联.
与其他肥胖指数相比,评估CVAI对事件HUA的预测性能.

主要方法:

利用来自中国健康与退休长度研究的5186名45岁以上的中国成年人的数据.
使用修改后的Poisson和后勤回归模型来评估与基线CVAI及其变化相关的事件HUA的风险和几率.
使用受限立方线用于剂量反应分析和AUC用于预测值评估.

主要成果:

在4年的随访期间,共确定了510起HUA事件.
较高的基线CVAI四分位数和每标准偏差的增加与增加的HUA风险显著相关 (RR分别为3.75和1.56).
CVAI的增加与HUA风险增加35%相关,而降低显示风险降低了34%.

结论:

基线CVAI,其变化和发展HUA的风险之间存在线性关联.
与其他五个肥胖指数相比,CVAI显示了事件HUA的优异预测性能.
CVAI是一个有价值的工具,用于识别患有高尿路血症风险较高的个体.

关键词:

中国的内脏脂肪指数.动态变化动态变化超性血症 (hyperuricemia) 是一种疾病,预期的队列研究.接收器的操作特征接收器的操作特征

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