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Updated: Jun 18, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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对针对法尔内索伊德X受体的新型自然激动剂进行计算研究

Xindan Hu1, Junliang Ge2, Ying Wen3

  • 1Department of Infectious Diseases, The First Affiliated Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.

Scientific reports
|July 30, 2024
PubMed
概括

确定了针对非酒精性脂肪肝炎 (NASH) 的法纳索伊德X受体 (FXR) 的新潜在药物. 两种新型化合物,ZINC000013374322和ZINC000006036327,显示出作为安全有效的FXR激动剂,副作用较少的承诺.

关键词:
发现工作室 发现工作室法尔内索伊德X受体 (FXR) 是一种非酒精性脂肪肝炎 (NASH) 是一种非酒精性脂肪肝炎.新型化合物 新型化合物肥酸 (OCA) 是一种肥酸.

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