外节自然杀手/T细胞淋巴瘤与桃体的参与:一个案例报告
Yang Xiao1, Xing Zhang2, Yingqin Gao1
1Department of Otolaryngology, Head and Neck Surgery, Children's Hospital Affiliated to Kunming Medical University (Kunming Children's Hospital), Kunming, China.
BMC oral health
|July 31, 2024
概括
一个罕见的婴儿突节自然杀手/T细胞淋巴瘤 (ENKTL) 病例.
科学领域:
- 儿科瘤学 儿科瘤学
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
背景情况:
- 涉及桃体的外节自然杀手/T细胞淋巴瘤 (ENKTL) 在儿科病例中非常罕见.
- 早期诊断和治疗对于儿科ENKTL的良好结果至关重要.
研究的目的:
- 报告一个罕见的儿童ENKTL病例,其中桃体受到影响.
- 要突出诊断和治疗的挑战和这个罕见的演示的结果.
主要方法:
- 一名13岁的女性出现了持续的喉痛,发烧和桃体炎.
- 诊断工作包括鼻镜,CT扫描,免疫组织化学 (CD2 +,CD3 +,CD4 +,CD5 +,CD8 +,粒酶B +,TIA-1 +) 和T细胞受体基因重组.
- 该患者接受了6个周期的SMILE化疗方案治疗.
主要成果:
- 组织病理学揭示了 tonsils 中的慢性 pyogenic 粒状炎症和 T 淋巴细胞.
- 免疫组织化学和基因重组证实ENKTL,第二阶段,桃体参与.
- 患者获得了对SMILE化疗的完全反应,在随访期间没有复发.
结论:
- 患有桃体的儿科ENKTL是一种罕见的实体,需要高度的怀疑指数.
- 微笑方案在治疗这种罕见的儿科ENKTL病例中表现出有效性.
- 完整的反应和没有复发的情况强调了化疗在儿科ENKTL的潜在有效性.
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