儿童肺肺:对文献的范围审查
Danilo Buonsenso1, Francesca Cusenza2, Lucrezia Passadore2
1Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. danilobuonsenso@gmail.com.
Italian journal of pediatrics
|July 31, 2024
概括
儿科肺炎,肺空间的,没有明确的最佳管理. 这次审查发现对治疗方法进行比较的证据有限,强调需要更好的儿科恩皮埃马试验.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 胸部外科手术 胸部外科手术
背景情况:
- 在社区获得的肺炎可以导致肺气,这是儿童严重的肺腔感染.
- 虽然并没有高致命性,但对于儿科恩皮埃马的最佳管理策略仍有争议.
- 目前的文献缺乏对抗微生物和外科手术进行强有力的比较.
研究的目的:
- 绘制有关儿科 empyema 的现有文献的地图.
- 为了确定研究类型,微生物学,疗法和患者的结果.
- 突出关于最佳儿科恩皮埃马管理的知识差距.
主要方法:
- 在PubMed和SCOPUS系统搜索2000年以来发表的关于儿科肺部血的研究.
- 遵守系统性审查和元分析的首选报告项目,扩展范围审查 (PRISMA ScR) 准则.
- 包括127项研究,包括各种研究设计和患者群体.
主要成果:
- 存在有限的比较研究,只有15项比较医疗与外科手术的方法,6项比较手术干预.
- 研究设计,纳入标准和治疗方法的异质性阻碍了关于最佳管理的最终结论.
- 总体死亡率为0.7% (78/10,896名儿童),亚洲和非洲的死亡率更高.
结论:
- 在了解儿科恩皮埃马病因,最佳的医疗和外科治疗以及新型抗生素的作用方面存在重大差距.
- 目前的证据基础不足以建立针对儿科 empyema 的最终治疗指南.
- 迫切需要精心设计的多国试验,采用严格的标准,以解决儿科恩皮埃马管理方面的知识差距.
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