胚胎带的胎镜释放基于证据-一个系统性审查
Fernando Ferrer-Marquez1,2, Jose L Peiro1,3, Gabriele Tonni4
1Center for Fetal and Placental Research, Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, Ohio, USA.
Prenatal diagnosis
|July 31, 2024
概括
胚胎带综合征 (ABS) 的胎儿手术显示出有前途的结果,高胎儿存活率和肢体功能保存. 然而,早产早产膜破裂 (PPROM) 是一个重要的并发症,需要进一步研究以进行最佳的患者选择.
科学领域:
- 围产儿医学 围产儿医学
- 胎儿外科手术 胎儿外科
- 遗传异常 是一种先天性异常.
背景情况:
- 羊带综合征 (ABS) 是一种先天性疾病,由羊带收缩胎儿部位引起.
- 管理ABS通常涉及解决潜在的胎儿并发症和四肢形.
研究的目的:
- 审查胎儿的周产期结局,这些胎儿经过胎儿外科手术来治疗羊带综合征 (ABS).
- 为了评估胎儿胚胎带释放的疗效和并发症.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在 MEDLINE,Embase,Scopus 和 Cochrane 图书馆的数据库中进行了搜索.
- 包括17项研究,其中37例ABS经受胎体释放.
主要成果:
- 手术时的中位妊娠年龄为22周.
- 在51.3%的病例中发生过早的膜破裂 (PPROM).
- 胎儿存活率为89.2%,肢体功能保存成功率为75.7%.
结论:
- 胚胎带的胎镜释放有效地保护肢体功能,并防止胎儿在ABS中死亡.
- 需要进一步的研究,以建立最佳的患者选择标准,因为相关的围产期并发症.
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