前列腺癌患者的减肥干预措施:一个范围审查
Karen Hye-Cheon Kim Yeary1, Han Yu1, Krista Varady2
1Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, United States.
Nutrition reviews
|July 31, 2024
概括
减肥干预措施有望改善前列腺癌患者的体重和组成. 需要对不同人群中的代谢生物标志物和癌症结果进行进一步的研究.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 基于证据的医学基于证据的医学.
背景情况:
- 前列腺癌患者经常经历体重变化影响他们的健康.
- 正在探索减肥干预措施以减轻这些影响.
研究的目的:
- 为前列腺癌患者进行减肥干预措施的范围审查.
- 评估对体重,身体组成,代谢生物标志物和癌症结果的影响.
主要方法:
- 系统性审查遵循系统性审查和元分析范围审查指南的首选报告项目.
- 在六个文献数据库中搜索相关研究.
- 包括饮食成分,体重作为结果和前列腺癌患者的研究.
主要成果:
- 包括12项研究,主要涉及美国白人男性.
- 大多数干预措施结合了饮食和体育活动,单独进行.
- 观察到体重和身体组成的显著改善,更长时间/剂量干预产生了更大的效果.
- 对代谢生物标志物和癌症结局的影响是混合的.
结论:
- 减肥干预可以积极影响前列腺癌患者的体重和组成.
- 需要对代谢和癌症特异性结果进行更多的研究.
- 未来的研究应侧重于多样化的患者群体和综合性结果措施.
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