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在COVID-19之后的视神经头部变化:基于光学连贯性断层扫描血管造影的纵向研究

Mojtaba Abrishami^1,2, Kiana Hassanpour³, Kia Bayat³

¹Eye Research Center, Khatam-al-Anbia Eye Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

The Journal of international medical research

|July 31, 2024

概括

冠状病毒疾病2019 (COVID-19) 可能会改变光神经头部 (ONH) 血管密度 (VD) 在辐射周毛细血管 (RPC) 网络. 这些变化,特别是在小血管中,表明COVID-19影响ONH血管在康复后.

科学领域:

眼科医生眼科眼科
血管生物学血管生物学
传染性疾病传染性疾病

背景情况:

冠状病毒疾病2019 (COVID-19) 是一种全球性流行病,具有潜在的长期健康影响.
视神经头部 (ONH) 是视觉的关键结构,含有易受血管变化的密集毛细血管网络.
光学连贯断层扫描血管学 (OCTA) 允许对视网膜和视神经头部微血管的非侵入性评估.

研究的目的:

在轻微的COVID-19感染后,研究周血管密度 (VD) 的纵向变化.
用OCTA评估COVID-19对视神经头部微血管系统的影响.

主要方法:

对已确认轻度COVID-19的健康个体进行前性纵向观察性研究.
使用Optovue RTVue XR Avanti OCTA进行的视觉神经头部 (ONH) 影像成像.
在恢复后的1个月和3个月,在辐射周毛细血管 (RPC) 网络中评估血管密度 (VD).

主要成果:

在整体ONH参数中没有观察到任何显著变化.
在中华人民共和国,发现了小型船只VD增加的显著趋势,特别是在特定的周围细胞区域.
在RPC内的所有血管VD中发现了显著的变化,盘内减少,下部区域增加.

结论:

COVID-19 感染可以影响视神经头部的辐射周毛细血管网络的血管密度.
这些发现凸显了COVID-19可能影响ONH血管的潜力,因此在临床评估中需要考虑.

关键词:

在 COVID-19 疫情中,视神经的头部视神经的头部新冠病毒疾病2019年光学连贯性断层扫描血管图谱辐射周毛细管毛细管网络船舶密度是指船舶的密度.

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