客观性缺血,主观性心痛和在心痛没有阻塞性冠状动脉疾病的情况下的心理痛苦
Yuting Liu1,2, Wei Jiang3, Haochen Wang2
1Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Center for Geriatrics Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology) Shenzhen Guangdong China.
心理压力测试显示,在没有阻塞性冠状动脉疾病 (ANOCA) 的胸痛患者中,心肌缺血的发病率更高. 较轻微的胸痛症状,而不是缺血严重程度,与ANOCA患者的心理健康状况较差相关.
科学领域:
- 心脏病学 心脏病学
- 妇女健康 妇女健康
- 精神病体医学是一种精神病体医学.
背景情况:
- 没有阻塞性冠状动脉疾病 (ANOCA) 的胸痛和没有阻塞性冠状动脉疾病的缺血是影响女性的普遍疾病.
- 以前的研究还没有充分区分这些疾病,也没有评估它们对心理健康的影响.
- 目标:使用各种诊断方法,将女性客观缺血的患病率与ANOCA进行比较,并评估客观和主观缺血对心理健康的影响.
研究的目的:
- 用多种非侵入性测试方式,比较被诊断患有无阻塞性冠状动脉疾病 (ANOCA) 的胸痛的女性客观缺血的患病率.
- 评估客观和主观缺血对患有ANOCA的女性心理健康的影响.
- 在这个患者群体中调查心痛严重程度,缺血检测和心理健康结果之间的关系.
主要方法:
- 84名ANOCA女性和42名对照女性接受了心理压力,药物压力,运动压力和霍尔特测试.
- 心肌缺血被客观地评估,使用正子发射断层扫描-计算机断层扫描和心电图.
- 用加拿大心血管学会 (CCS) 尺度对主观心痛症状进行了分级,心理评估使用了六个标准化尺度.
主要成果:
- 精神压力测试在44%的ANOCA患者中发现了缺血,比药物测试 (28.6%),运动测试 (21.2%) 或霍尔特测试 (32.9%) 高.
- 在完成所有测试的患者中,30%没有表现出缺血症,所有测试中只有1.9%表现出缺血症.
- 与对照组相比,ANOCA患者的心理痛苦得分高于对照组. 轻度心痛 (CCS I) 与焦虑,抑郁,感知压力和D型人格特征的增加有关,独立于客观缺血发现.
结论:
- 在ANOCA患者心肌缺血的诊断产量在不同的非侵入性检测方法之间有显著差异.
- 在ANOCA患者中,心理状况的恶化与心痛症状的严重程度比与客观性缺血的存在或程度更强烈相关.
- 对ANOCA患者的临床护理应优先考虑症状管理和心理支持,认识到主观痛经历对心理健康的重大影响.
更多相关视频
10:28Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
相关概念视频
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Psychological Responses to Stress
Antianginal Drugs: Nitrates and β-Blockers
Organic nitrates, such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Antianginal Drugs: Calcium Channel Blockers and Ranolazine
CCBs, a diverse class that includes dihydropyridines (nifedipine) and diphenylalkylamines (verapamil and diltiazem), exert their effect by blocking calcium channels in cardiac and smooth muscle cells. This...
