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确定手术后持久高血压的危险因素,在患有染细胞瘤的患者
Shiyang Lu1, Chao Wang1, Xueyan Tian1
1Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China.
Journal of surgical oncology
|July 31, 2024
概括
年龄较大,高血压持续时间较长和心血管事件是染细胞瘤手术后持续高血压的关键风险因素. 识别这些因素有助于更好的患者管理和后续策略.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 心血管医学 心血管医学
背景情况:
- 乳红细胞瘤 (上腺的罕见瘤) 主要通过手术切除来治疗.
- 很大一部分患者甚至在成功的腎上腺切除术后也会经历持续性高血压.
- 导致这种术后高血压的危险因素仍然不完全理解.
研究的目的:
- 为了确定持续高血压的独立风险因素,在患有上腺切除术后的染细胞瘤的患者.
- 为改善这些患者的术后管理和长期随访策略提供信息.
主要方法:
- 在2007年至2018年期间,对259名因发红细胞瘤而接受上腺切除术的患者进行了回顾性分析.
- 收集和分析患者人口统计,并发病症和外科手术期间的数据.
- 使用二进制后勤回归和接收器运行特征 (ROC) 曲线分析来确定风险因素和切割值.
主要成果:
- 40.9%的患者出现了术后持续性高血压.
- 确定的独立风险因素包括年龄 (OR=1.16),高血压持续时间 (OR=3.10) 和心血管事件的存在 (OR=17.17).
- 确定最佳切断值为66岁的年龄和27个月的高血压持续时间.
结论:
- 高龄,长期高血压和同时发生的心血管事件是持续性高血压的显著预测因素.
- 这些发现对于完善术前风险分层和术后护理方案至关重要.
- 对这些风险因素的更好理解可以导致更个性化和更有效的管理计划.
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