在平民中对DSM-5 (PCL-5) 的PTSD-Checklist进行基于集群的分析,这些平民患有脑震荡后认知变化
Erik A Fraunberger1, Alison J Wilson1, Adam Idriss1
1Department of Clinical Neurosciences, Division of Physical Medicine & Rehabilitation, University of Calgary, Calgary Alberta, Canada.
Brain injury
|July 31, 2024
概括
创伤后应激障碍 (PTSD) 症状与持续性脑震荡后症状 (PPCS) 中的认知缺陷相关. 具体来说,较高的PTSD兴奋度和反应性得分与命名和抽象任务的表现较差有关.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 脑损伤后持续的脑震荡后症状 (PPCS) 可以显著影响认知功能.
- 在PPCS患者中,创伤后应激障碍 (PTSD) 症状和认知障碍之间的相互作用需要进一步调查.
研究的目的:
- 探索成年人被诊断患有PPCS的PTSD症状和认知能力之间的关系.
- 在这个人群中确定与认知缺陷相关的特定PTSD症状集群.
主要方法:
- 患有PPCS的成年人完成了DSM-5 (PCL-5),GAD-7和PHQ-9的PTSD检查清单.
- 使用蒙特利尔认知评估 (MoCA) 选认知功能.
- 使用多重回归和逻辑回归分析来确定PTSD症状和MoCA分数之间的关联,并根据相关的共变量进行调整.
主要成果:
- 在MoCA得分和PCL-5 (PTSD症状) 和PHQ-9 (抑郁症状) 得分之间观察到显著的负相关性.
- 在PCL-5的兴奋和反应性集群中,较高的得分与MoCA测量的命名和抽象推理任务的表现较差有关.
结论:
- 这些发现表明,PTSD症状集群,特别是与兴奋和反应相关的症状,与PPCS患者的特定认知缺陷有关.
- 这些关联可能表明旨在改善PPCS和并发性PTSD症状患者认知功能的干预措施的潜在治疗目标.
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