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Updated: Jun 18, 2025

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
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用循环离子流动性质谱法对治疗性寡核酸同位素杂质的分离和鉴定

Shogo Omuro1, Takao Yamaguchi1, Taiji Kawase2

  • 1Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

Journal of the American Society for Mass Spectrometry
|July 31, 2024
PubMed
概括

循环离子移动性质谱 (IMS) 有效地分离和表征治疗性寡核酸异构体,包括诸如缩短剂和改性形式等杂质. 这种方法提高了新型寡核酸治疗的质量控制.

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