对外听道的转移:系统性审查
Madison V Epperson1, Arushi Mahajan2, Christopher M Welch1
1Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.
概括
扩散到外部听道 (EAC) 是罕见的,经常出现听力损失和耳痛. 通过活检进行早期诊断对于干预至关重要,因为预后很差,平均存活时间为4.5个月.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
背景情况:
- 对外听道 (EAC) 的转移是一种不常见的瘤事件.
- 了解其行为,诊断,管理和死亡率对于患者的治疗结果至关重要.
研究的目的:
- 系统地审查有关EAC转移的行为,诊断,管理和死亡率的文献.
- 确定区分EAC转移与其他骨亚部位干涉的关键特征.
主要方法:
- 通过使用PubMed/Medline,EMBASE和Web of Science进行了系统的文献审查.
- 包括1948年至2023年6月发表的关于EAC转移的研究,数据进行了定性合成.
主要成果:
- 32项研究确定了37名患有EAC转移的患者,主要是男性 (73%),平均年龄为58岁.
- 常见的原发性瘤包括血液恶性瘤,乳腺,食道,脏和前列腺癌.
- 经诊断后EAC转移的中位时间为18个月,平均存活时间为4.5个月;症状包括听力损失和耳痛.
结论:
- 外耳道转移与其他骨部位相比呈现独特的特征.
- 通过活检及时诊断对于及时干预和管理至关重要.
- 整体预后不佳,转移诊断后的平均存活时间为4.5个月.
相关概念视频
Anatomy of the Ear
8.0K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
8.0K
Auditory Pathway
5.4K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.4K
The Auditory Ossicles
1.6K
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
1.6K


