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Updated: Jun 18, 2025

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亚酸通过促进PICK1 BAR域同位素的形成来诱导侵袭性形成

John Ho Chun Lai1,2, Marianthi Tsogka1, Jun Xia1,3

  • 1Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

Molecular biology of the cell
|July 31, 2024
PubMed
概括

酸酸盐诱导了侵略体的形成,这种结构将错误折叠的蛋白质隔离起来,这与神经退行性疾病有关. 与C酶1 (PICK1) 相互作用的蛋白显示了对这些侵略体的条件局部化,这表明它在疾病中发挥了作用.

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Protein Complex Assembly02:41

Protein Complex Assembly

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