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Updated: Jun 18, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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慢性病毒感染改变了细胞毒性CD8+ T细胞中PD-1位点的亚核定位

Catarina Sacristán1, Ben A Youngblood2, Peiyuan Lu3

  • 1Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, USA.

Cell reports
|July 31, 2024
PubMed
概括

在慢性感染期间,特定于病毒的CD8+ T细胞变得耗尽,并升高调节编程死亡-1 (PD-1). 这项研究揭示了PD-1基因在核内部的局部化变化,影响T细胞疲劳.

关键词:
飞-1 飞-1 飞-1 飞-1CD8 (((+) T细胞是T细胞中的一个.CP: 免疫学 免疫学在L-selectin中进行选择.在PD-1中使用PD-1.慢性病毒感染 慢性病毒感染细胞毒性 细胞毒性疲 疲 疲 是一种疲.甲基化处理 甲基化处理亚核局部化局部化转录 转录 是一种转录.

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