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Updated: May 13, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
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来自真菌病原体Cryptococcus neoformans的Trehalose-6-phosphate合成酶,Tps1的结构:一种抗真菌的目标

Erica J Washington1, Ye Zhou2, Allen L Hsu3

  • 1Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710.

Proceedings of the National Academy of Sciences of the United States of America
|July 31, 2024
PubMed
概括

研究人员阐明了一个关键酶的结构,Cryptococcus neoformans Tps1,对于真菌生存至关重要. 这种结构性洞察力可能会导致针对三糖生物合成的新型抗真菌药物.

关键词:
这是Cryptococcus.基底基因基因基因基因基因低温电子显微镜的使用方法菌类病原体的真菌病原体这是一种三糖.

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