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Updated: Jun 16, 2026

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多作用Pt (IV) 复合体:卵巢癌细胞系中的细胞毒性和机制研究

Leila Tabrizi1,2, Alan M Jones3, Isolda Romero-Canelon3,4

  • 1School of Biological and Chemical Sciences, University of Galway, Galway H91 TK33, Ireland.

Inorganic chemistry
|July 31, 2024
PubMed
概括

新的 (IV) 复合物对卵巢癌细胞表现出强烈的活性. 复合体2有效地克服了西斯普拉丁耐药性,并通过DNA损伤和ROS生成诱导了细胞亡.

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Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...