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Updated: Jun 18, 2025

DNA-affinity-purified Chip DAP-chip Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
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Published on: July 21, 2014

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对细菌DSR2抗菌体防御系统NADase上的激活机制的结构洞察力

Hong Zhang1, Yu Li2,3, Lanlan Li1

  • 1Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation and Fujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou 350117, PR China.

Science advances
|July 31, 2024
PubMed
概括

防御相关的sirtuin2 (DSR2) 通过控制尼古丁胺氨酸二核酸 (NAD+) 水平来调节细菌的抗菌体防御. 它的活性由尾管蛋白 (TTP) 和DSAD1调节,揭示了关键的分子机制.

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