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CED-5/CED-12 (DOCK/ELMO) 可以通过不同的动机促进和抑制F-actin的形成,这些动机可能针对不同的GTPases

Thejasvi Venkatachalam1, Sushma Mannimala1, Yeshaswi Pulijala1

  • 1Department of Pathology and Laboratory Medicine, Rutgers-Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America.

PLoS genetics
|July 31, 2024
PubMed
概括

研究人员发现,CED-5/CED-12蛋白在C. elegans胚胎发育过程中调节F-actin动态. 这些蛋白质可以促进和抑制F-actin,这取决于它们的特定域和向GTPases,影响细胞迁移和尸体吞.

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